Statistician – IVAC Research Programme Non-profit Jobs – Medical Research Council (MRC) UK / UVRI

Organization: Medical Research Council (MRC) UK / UVRI 
Duty Station: Entebbe, Uganda
Reports to:  Head of Statistics & Head of the Immunomodulation and Vaccines research
Position Code: STAT518

About US:
The MRC/UVRI Uganda Virus Research Unit on AIDS was established following a request in 1988 from the Uganda Government to the British Government for collaboration on the research of HIV (Human Immunodeficiency Virus) infection and AIDS (Acquired Immunodeficiency. The Unit is a center of excellence in HIV/AIDS related research. It conducts large-scale epidemiological and intervention studies, clinical trials, virological and immunological research and behavioural studies, and has generated a wealth of research results that have been used to inform policy and practice that have led to a large number of scientific publications in peer reviewed journals over time.

About the Research Programme:
The principal goal of the research programme that the post-holder will be working within is to understand the impact of infection exposure on human immunological programming and health. Our overarching hypothesis is that chronic and cumulative infection exposure influences immunological mechanisms through active processes (during current infection), lasting epigenetic modifications, and genetic selection; that (therefore) some effects do not immediately respond to treatment; and that effects critically impact upon major health outcomes including vaccine responses and susceptibility to pathogens, allergy-related disease and metabolic conditions. The main focus of our new work is on vaccines, addressing the role of infectious exposures in population differences in vaccine immunogenicity. We are also continuing our long-standing programme of allergy-related and metabolic studies.

Job Summary: The main responsibilities of the Statistician - IVAC Research Programme will be to provide statistical support in the design and conduct of clinical trials, epidemiological studies and community-based interventions carried out by the programme, and to carry out statistical analysis of data from these projects and prepare the results for publication. The post holder will be a member of the Unit's Statistics and Data Management section which currently has eight statisticians (including three PhD candidates), and over 30 other data personnel who work in data management, programming, transcription and archiving. The section enjoys close links with the Tropical Epidemiology Group at the London School  of Hygiene and Tropical Medicine and works closely with statisticians and epidemiologists from this group in London. The post-holder will work closely together with one senior statistician in particular from this group who has worked together with the Head of the IVAC Programme for many years. The post-holder will be expected to make occasional visits to our study clinics, sites and communities and s/he may occasionally be required to stay overnight at one of our research stations around Uganda. There may also be occasional travel to take part in conferences or meeting nationally and internationally. The post holder will also be encouraged to contribute to the Unit's training and teaching activities and will be expected to provide statistical support and advice to the research programme's lab technicians, project leaders and PhD candidates.
You will be responsible to the Head of the Immunomodulation and Vaccines research programme and the Head of Statistics section.

Key Duties and Responsibilities: 
  • Provide statistical support for studies carried out by the research programme, and in particular to assist with issues relating to study design, sampling and field procedures, quality control activities, data collection and statistical analysis;
  • Work closely with data managers and provide a statistical perspective on designing and setting up study databases and data processing;
  • Carry out statistical analysis of project-collected data;
  • Actively contribute to the development and preparation of protocols and data collection instruments for new research studies;
  • Formulate develop statistical analysis plans for ongoing trials and to organise and prepare for milestone events such as database lock, unblinding, analysis and reporting;
  • Prepare regular views on study data to help project management teams monitor recruitment and other data flows and data quality issues during the conduct of a study;
  • Carry out interim analyses for data monitoring committees and trial steering committees;
  • Prepare scientific reports and present results in meetings with colleagues and collaborators;
  • Actively contribute to scientific articles and prepare publication-standard tables and figures;
  • Support and advise project leaders and lab technicians on statistical issues as well as other scientists within the Unit as appropriate;
  • Perform any other additional tasks as required by the principal investigator or Head of Medical Statistics.

Qualifications, Skills and Experience:
  • The applicant for the Medical Research Council (MRC) UK / UVRI Statistician - IVAC Research Programme job placement must hold a Master’s degree in statistics (post-graduate qualifications in epidemiology, mathematics or equivalent data-related field with a strong statistical analysis component will also be considered);
  • Practical experience as an applied medical statistician, including with the analysis of large datasets;
  • Strong statistical analysis skills and a good understanding of statistical issues in medical research;
  • Strong statistical programming skills using STATA or equivalent statistical analysis software;
  • Good computer skills including proficiency with Microsoft Office applications and in particular with Excel and Word;
  • Keen attention to detail
  • Excellent written and oral communication skills in English;
  • Strong organisational skills
  • Good team working skills
  • Previous experience in the design and analysis of clinical trials is desirable
  • Knowledge or experience of epidemiology and public health.
  • Experience working with specialised database software such as OpenClinica, ODK, REDCap, Access or similar;
  • Record of scientific publications in peer-reviewed journals;

Personal Competencies:
  • Personal Integrity
  • Emotional Resourcefulness
  • Ability to Learn
  • Forward Thinking
  • Reliability
  • Openness to Others
  • Independence
  • Analytical Thinking
  • Conceptual Thinking
  • Pro-activity
  • Results Orientation
  • Thoroughness
  • Concern for Excellence
  • Flexibility towards Others
  • Service Orientation
  • Development Orientation
  • Ability to Multi - Task

How to Apply:
The candidates should send their application letters, curriculum vitae including names, email addresses and telephone contact details of three (3) referees, plus copies of academic qualifications should be e-mailed to NB: Please quote the following position code in the subject line of the email: Statistician - STAT518. Please also fill the following online form accordingly after submitting the application documents on the e-mail above. Click Here

Address to:
The Human Resource and Administration Manager
MRC/ UVRI and LSHTM Uganda Research Unit
P.O. Box, 49 Entebbe.

NB: Only shortlisted candidates will be contacted for interviews. Note that academic qualifications will be subjected to verification by the issuing institutions. Please note that the Unit became part of the London School of Hygiene and Tropical Medicine effective 1st February 2018.

Deadline: 8th June 2018

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